|
KMID : 0356919770100010065
|
|
Korean Journal of Anesthesiology
1977 Volume.10 No. 1 p.65 ~ p.70
|
|
|
Changes in Serum Potassium after Induction with Propanidid-SuecinyIcholine
|
|
趙裕永/Cho, Yoo Young
崔玲/吳興根/曺正鉉/Choi, Ryung/Oh, Hung Kun/Cho, Chung Hyun
|
|
|
Abstract
|
|
|
Three groups of healthy adults were premedicated with diazepam or secobarbital and anesthetized with propanidid or thiopental. The concentration of serum potassium was measured before induction and after succinylcholine iodide administraion.
The increases of potassium in diazepam-thiopental, diazepam-propanidid and secobarbital-propanidid groups were 0.14, 0.06, and 0.11mEq/L (3.29, 1.38 and 2.58%) respectively.
Serum potassium changes were least in diazepam-propanidid group, but there were no significant differences among the 3 groups.
The choice of induction agent is of importance for the changes in serum potassium which follow the subsequent injection of succinylcholine iodide. For instance, intravenous induction by barbiturate is followed by a lesser increase in serum potassium after succinylcholine injection than induction by halothane. As barbiturates are so commonly used as intravenous induction agents, we chose thiopental and succinylcholine iodide as standard with which to compare the other induction agents, propanidid and succinylcholine iodode. And also, we wanted compare two premedicants, secobarbital and diazepam.
The results were as followes:
(1) The thiopental-succinylcholine iodide group and the propanidid-succinylcholine iodide group revealed no significant differences in serum potassium level.
(2) There was a lesser increase in serum potoassium level after premedication with diazepam than premedication with secobarbital in the propanidid-succinylcholine iodide group.
(3) Induction by propanidid succinylcholine iodide and premedication by diazepam are recommendable for least increasing the serum potassium level.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
   
|
|